| 2025-02-02 16:00:02February 2, 2025 |   Nairobi City Stars Vs AFC Leopards | 16:00:024:00 pm | Kenyatta Stadium, Machakos | - |
| 2025-02-09 15:00:08February 9, 2025 |  AFC Leopards Vs Kariobangi Sharks | 15:00:083:00 pm | Dandora Stadium | - |
| 2025-02-19 03:00:06February 19, 2025 |  Mara Sugar Vs AFC Leopards | 03:00:063:00 am | Raila Odinga Stadium, Homabay | - |
| 2025-02-23 15:00:56February 23, 2025 |  AFC Leopards Vs Sofapaka FC | 15:00:563:00 pm | Dandora Stadium | - |
| 2025-03-01 15:00:59March 1, 2025 |  AFC Leopards Vs Shabana FC | 15:00:593:00 pm | Kenyatta Stadium, Machakos | - |
| 2025-03-02 15:00:07March 2, 2025 |  Kenya Police FC Vs AFC Leopards | 15:00:073:00 pm | Police Sacco Grounds | - |
| 2025-03-08 15:00:04March 8, 2025 |  AFC Leopards Vs Kakamega Homeboyz | 15:00:043:00 pm | Kenyatta Stadium, Machakos | - |
| 2025-04-06 15:00:37April 6, 2025 |  Gor Mahia Vs AFC Leopards | 15:00:373:00 pm | Nyayo National Stadium | - |
| 2025-04-09 15:00:52April 9, 2025 |  Posta Rangers Vs AFC Leopards | 15:00:523:00 pm | Dandora Stadium | - |
| 2025-04-13 15:00:56April 13, 2025 |  AFC Leopards Vs Bidco United | 15:00:563:00 pm | Dandora Stadium | - |
| 2025-04-19 15:00:00April 19, 2025 |  Tusker FC Vs AFC Leopards | 15:00:003:00 pm | Kenyatta Stadium, Machakos | - |
| 2025-05-03 15:00:20May 3, 2025 |  AFC Leopards Vs Ulinzi Stars | 15:00:203:00 pm | Kenyatta Stadium, Machakos | - |
| 2025-05-10 15:00:37May 10, 2025 |  AFC Leopards Mathare United | 15:00:373:00 pm | Kenyatta Stadium, Machakos | - |
| 2025-05-18 15:00:58May 18, 2025 |  Bandari FC Vs AFC Leopards | 15:00:583:00 pm | Mbaraki Sports Ground, Mombasa | 32 |
| 2025-06-14 15:00:49June 14, 2025 |  FC Talanta Vs AFC Leopards | 15:00:493:00 pm | Kenyatta Stadium, Machakos | 33 |
| 2025-06-22 15:00:48June 22, 2025 |  AFC Leopards Vs KCB FC | 15:00:483:00 pm | Nyayo National Stadium | - |
